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Buy 1P-LSD itself is a research chemical psychedelic closely related to LSD-25. It is available in blotter and liquid form. It has a 67-fold lower binding capacity for 5-HT1A receptors, 13-fold less activity at 5-HT2A receptors, and a 3.5-fold increase at h5-HT2C receptors than LSD-25. However, 1P-LSD is a prodrug of LSD, which means that it is converted by the liver to LSD, which then produces psychoactive effects.
1P-LSD stands for 1-propionyl-lysergic acid diethylamide. It’s a derivative of LSD which essentially means it’s a modified version of the classic LSD-25 that Albert Hofmann discovered in 1943. This molecule is differentiated from LSD by a propionyl group attached to the nitrogen molecule in the indole portion of LSD. The central indole molecule of LSD is the characterizing element of the molecule that’s shared with all other tryptamine-based psychedelics (such as DMT or psilocybin).
1P-LSD itself is only mildly psychedelic. It has a 67-fold less binding affinity for the 5-HT1A receptors, 13-fold less activity at the 5-HT2A receptors, and a 3.5-fold increase at h5-HT2C receptors than LSD-25.
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